| |
|
Patient |
| |
Infusion dose |
1 |
2 |
3 |
4 |
| D1 |
Omegaven® (mL) |
125 |
110 |
100 |
145 |
| |
Protocol (mL/kg): 1.5 |
1.5 |
1.5 |
1.5 |
1.5 |
| |
EPA (g) |
2.6 (1.6-3.5) |
2.2 (1.4-3.1) |
2.0 (1.3-2.8) |
3.0 (1.8-4.1) |
| D3 |
Omegaven® (mL) |
185 |
170 |
50 |
70 |
| Protocol (mL/kg): 2.25 |
2.25 |
2.25 |
0.75 |
0.75 |
| EPA (g) |
3.8 (2.3-5.2) |
3.5 (2.1 – 4.8) |
1.0 (0.6 – 1.4) |
2.9 (0.9 – 2.0) |
| D5 |
Omegaven® (mL) |
245 |
225 |
0 |
70 |
| Protocol (mL/kg): 3 |
3 |
3 |
0 |
0.75 |
| EPA (g) |
5.0 (3.1-6.9) |
4.6 (2.8-6.4) |
0 |
1.4 (0.9 – 2.0) |
| D8 |
Omegaven® (mL) |
245 |
225 |
0 |
0 |
| Protocol (mL/kg): 3 |
3 |
3 |
0 |
0 |
| EPA (g) |
5.0 (3.1-6.9) |
4.6 (2.8-6.4) |
0 |
0 |
| D10 |
Omegaven® (mL) |
245 |
225 |
0 |
0 |
| Protocol (mL/kg): 3 |
3 |
3 |
0 |
0 |
| EPA (g) |
5.0 (3.1-6.9) |
4.6 (2.8-6.4) |
0 |
0 |
| D12 |
Omegaven® (mL) |
0 |
225 |
0 |
0 |
| Protocol (mL/kg): 3 |
0 |
3 |
0 |
0 |
| EPA (g) |
0 |
4.6 (2.8-6.4) |
0 |
0 |
| Total EPA (g) |
21.3 (13.1-29.5) |
24.0 (14.8-33.3) |
3.1 (1.9-4.2) |
5.8 (3.4-8.0) |
| Total EPA (g/24 h) |
2.1 (1.3 – 3.0) |
1.7 (1.1-2.4) |
1.0 (0.6-1.4) |
1.2 (0.7-1.6) |
|
