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Figure 1: Genistein stimulation of LDLR expression at the transcriptional level. HepG2 cells were serum-starved and then stimulated with genistein. Protein levels of LDLR in response to 1, 5, 10 and 20 µM of genistein for 24 h (A), changes in protein (B) and mRNA levels (C) of LDLR after incubation with 10 µM of genistein within 24 h. Results are expressed as mean ± SD of at least three independent experiments. Different letters (a-c) represent significant differences (p<0.05) between all groups by ANOVA. |