| Groups
|
GSH
(mg %) |
SOD
(U/g Hb) |
GPx
(U/g Hb) |
CAT
(U/g Hb) |
| Normal (1 ml saline) |
24.66 ± 2.30 |
27.50 ± 4.11 |
114.46 ± 6.49 |
7.83 ± 1.07 |
| Control (ISO, 85 mg/kg) |
11.72 ± 1.57* |
12.64 ± 2.25* |
58.17 ± 7.11* |
4.64 ± 0.79* |
| Astaxanthin (50 mg/kg) + ISO (85 mg/kg) |
14.55 ± 2.14@ |
17.60 ± 3.81@ |
72.25 ± 4.46@ |
5.22 ± 0.58@ |
| Astaxanthin (100 mg/kg) + ISO (85 mg/kg) |
22.92 ± 3.05* |
23.42 ± 2.35* |
95.16 ± 5.60* |
7.08 ± 1.36* |
| Vitamin C (1 g/kg,b.w) + ISO (85 mg/kg) |
18.35 ± 2.88* |
21.50 ± 4.20* |
84.15 ± 6.09* |
6.25 ± 0.60@ |
Isoproterenol was given subcutaneously as a single dose of 85 mg/kg.b.w. to 18 h fasted animals. It was given to all groups except the normal one. astaxanthin (50 and 100
mg/kg) were orally given daily for 58 days and the last dose of each was given 1 h before Isoproterenol administration. Blood samples were collected 24 h after isoproterenol
administration. Activity is expressed as: 50% of inhibition of pyrogallol autooxidation per min for SOD and the obtained values were divided by the haemoglobin (Hb)
concentration. Values are given as mean ± SD for groups of eight animals each.
* Significantly different from normal group at p<0.01. @ Significantly different from control group at p<0.05. |
