Groups |
CK-MB(U/L) |
LDH(IU/L) |
ALT(IU/L) |
AST (IU/L) |
Normal (1 ml saline) |
63.46 ± 4.65 |
126.45 ± 7.43 |
25.16 ± 2.30 |
32.64 ± 3.40 |
Control (ISO, 85 mg/kg) |
526.75 ± 11.37* |
243.85 ± 9.44* |
42.66 ± 1.35* |
57.33 ± 4.11* |
Astaxanthin (50 mg/kg) + ISO (85 mg/kg) |
282.25 ± 10.55@ |
205.61 ± 11.36@ |
35.18 ± 2.40@ |
46.22 ± 3.53@ |
Astaxanthin (100 mg/kg) + ISO (85 mg/kg) |
210.30 ± 9.86* |
143.56 ± 7.18* |
28.24 ± 3.06* |
37.48 ± 3.50* |
Vitamin C (1 g/kg,b.w) + ISO (85 mg/kg) |
235.12 ± 7.65* |
152.33 ± 9.40* |
31.25 ± 1.53* |
40.64 ± 2.57* |
Isoproterenol was given subcutaneously as a single dose of 85 mg/kg.b.w. to 18 h fasted animals. It was given to all groups except the normal one. astaxanthin (50 and 100
mg/kg) were orally given daily for 58 days and the last dose of each was given 1 h before Isoproterenol administration. Blood samples were collected 24 h after isoproterenol
administration. Values are given as mean ± SD for groups of eight animals each.
* Significantly different from normal group at p<0.01. @ Significantly different from control group at p< 0.05. |