| Molecular target of resveratrol |
Expression changes by resveratrol treatment |
Cellular responses by resveratrol treatment |
References |
| NF-κβ |
Down-regulation |
Result in apoptosis and cell cycle arrest |
[81,159] |
| p53 |
Up-regulation |
Induce apoptosis |
[80] |
| HSF-1 |
Down-regulation |
Inhibit expression of survivin |
[99] |
| AP-1 |
Down-regulation |
Cell cycle G1 arrest |
[159] |
| hTERT |
Down-regulation |
Inhibit telomerase activity |
[97] |
| Bax |
Up-regulation |
Induce apoptosis |
[78,79] |
| Bcl-2 |
Down-regulation |
Induce apoptosis |
[77,79,81] |
| SIRT1/Sir2 |
Up-regulation |
Result in de-acetylation of key genes |
[104,114,122] |
| Survivin |
Down-regulation |
Result in apoptosis |
[98] |
|
