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Figure 4: Visible light (A) and fluorescence (B, 655nm) images of a mouse bearing a subcutaneous M21 melanoma tumor 45minutes after injection of carboxy-PEG coated QD’s directly into the tumor. The image highlights how the sentinel lymph nodes that the tumor drains into can be readily identified. (From: Sentinel Lymph Node Imaging Using Quantum Dots in Mouse Tumor Models – Ballou, B – Bioconjugate Chemistry 2007)[101]. |