| Characteristic | No. | Hazard ratio (95% CI) | p value for intervention (ANOVA) | p value for interaction | |
| Sex, no. of patients | 0.80 | ||||
| Male | 0.96 | ||||
| Nano | 49 |  |
0.92 (0.73 to 1.06) | ||
| Ferro | 44 | |
0.89 (0.69 to 1.09) | ||
| Stent | 46 | |
0.92 (0.76 to 1.07) | ||
| Female | 0.79 | ||||
| Nano | 11 | |
0.78 (0.49 to 0.99) | ||
| Ferro | 16 | |
0.85 (0.56 to 1.05) | ||
| Stent | 14 | |
0.89 (0.63 to 1.06) | ||
| Smoking, no. | 0.27 | ||||
| Never | 0.09 | ||||
| Nano | 9 | |
0.75 (0.64 to 0.94) | ||
| Ferro | 11 | |
0.57 (0.43 to 0.98) | ||
| Stent | 7 | |
0.62 (0.59 to 0.88) | ||
| Stopped/ Current | 0.89 | ||||
| Nano | 51 | |
0.89 (0.76 to 1.19) | ||
| Ferro | 49 | |
0.81 (0.68 to 1.14) | ||
| Stent | 53 | |
0.87 (0.72 to 1.19) | ||
| Alcohol abuse, no. | 0.97 | ||||
| Yes | 0.94 | ||||
| Nano | 29 | |
0.57 (0.36 to 1.01) | ||
| Ferro | 37 | |
0.69 (0.45 to 0.87) | ||
| Stent | 25 | |
0.64 (0.33 to 0.94) | ||
| No | 0.98 | ||||
| Nano | 31 | |
0.93 (0.59 to 1.12) | ||
| Ferro | 23 | |
0.87 (0.85 to 1.11) | ||
| Stent | 35 | |
0.85 (0.69 to 1.06) | ||
| Baseline PAV, % | 0.79 | ||||
| < Mean | 0.97 | ||||
| Nano | 22 | |
0.89 (0.66 to 1.01) | ||
| Ferro | 21 | |
0.85 (0.58 to 0.98) | ||
| Stent | 26 | |
0.86 (0.55 to 0.93) | ||
| ≥ Mean | 0.78 | ||||
| Nano | 38 | |
0.43 (0.16 to 0.49) | ||
| Ferro | 39 | |
0.32 (0.01 to 0.62) | ||
| Stent | 34 | |
0.38 (0.09 to 0.72) | ||
| Baseline MLD, mm | 0.84 | ||||
| < Mean | 0.72 | ||||
| Nano | 36 | |
0.32 (0.16 to 0.73) | ||
| Ferro | 33 | |
0.39 (0.04 to 0.58) | ||
| Stent | 31 | |
0.49 (0.34 to 0.69) | ||
| ≥ Mean | 0.92 | ||||
| Nano | 24 | |
0.69 (0.49 to 0.87) | ||
| Ferro | 27 | |
0.75 (0.58 to 0.77) | ||
| Stent | 29 | |
0.77 (0.54 to 0.94) | ||
| Baseline calcium, mm2* | 0.97 | ||||
| < Mean | 0.99 | ||||
| Nano | 28 | |
0.74 (0.54 to 0.85) | ||
| Ferro | 23 | |
0.69 (0.58 to 0.88) | ||
| Stent | 25 | |
0.76 (0.54 to 0.86) | ||
| ≥ Mean | 0.96 | ||||
| Nano | 32 | |
0.49 (0.37 to 0.61) | ||
| Ferro | 37 | |
0.53 (0.39 to 0.66) | ||
| Stent | 35 | |
0.64 (0.54 to 0.68) | ||
| Baseline necrotic core, mm2* | 0.047 | ||||
| < Mean | 0.031 | ||||
| Nano | 36 | |
0.46 (0.39 to 0.49) | ||
| Ferro | 39 | |
0.58 (0.52 to 0.71) | ||
| Stent | 33 | |
0.74 (0.64 to 0.85) | ||
| ≥ Mean | 0.048 | ||||
| Nano | 24 | |
0.73 (0.56 to 0.98) | ||
| Ferro | 21 | |
0.87 (0.76 to 0.97) | ||
| Stent | 27 | |
0.39 (0.34 to 0.72) | ||
| Baseline fibrous, mm2* | 0.63 | ||||
| < Mean | 0.41 | ||||
| Nano | 28 | |
0.56 (0.36 to 0.86) | ||
| Ferro | 23 | |
0.37 (0.14 to 0.53) | ||
| Stent | 24 | |
0.54 (0.34 to 0.78) | ||
| ≥ Mean | 0.69 | ||||
| Nano | 32 | |
0.55 (0.35 to 0.80) | ||
| Ferro | 37 | |
0.48 (0.28 to 0.70) | ||
| Stent | 36 | |
0.56 (0.37 to 0.63) | ||
| Baseline fibro-fatty, mm2* | 0.068 | ||||
| < Mean | 0.83 | ||||
| Nano | 29 | |
0.75 (0.55 to 1.01) | ||
| Ferro | 26 | |
0.78 (0.50 to 0.99) | ||
| Stent | 24 | |
0.79 (0.53 to 0.93) | ||
| ≥ Mean | 0.049 | ||||
| Nano | 31 | |
0.75 (0.61 to 1.06) | ||
| Ferro | 34 | |
0.54 (0.35 to 0.68) | ||
| Stent | 36 | |
0.69 (0.55 to 1.01) |
PAV regression below 40% Glagov threshold PAV regression above 40% Glagov threshold
