| Parameter |
Methocel E15 Blank Film |
Methocel E15 + BSA nanoemulsion |
CMCs Blank Film |
CMCs 8% + BSA nanoemulsion |
| pH |
7.10 ± 0.02 |
6.88 ± 0.02 |
8.55 ± 0.02 |
7.45 ± 0.03 |
| Viscosity (cps)* |
875.00 ± 0.00 |
1206.67 ± 2.89 |
520.00 ± 0.00 |
842.67 ± 2.89 |
| Thickness (mm) |
0.052 ± 0.005 |
0.093 ± 0.004 |
0.049 ± 0.004 |
0.099 ± 0.005 |
| Weight Variance (mg) |
54.70 ± 0.20 |
81.90 ± 0.40 |
55.27 ± 0.25 |
84.13 ± 0.12 |
| Folding Endurance (times) |
> 300 |
> 300 |
> 300 |
> 300 |
| Disintegration Time (seconds) |
59.33 ± 1.53 |
83.67 ± 1.53 |
14.67 ± 3.06 |
32.67 ± 1.53 |
| Dissolution Time (seconds) |
155.00 ± 2.65 |
184.67 ± 2.52 |
92.00 ± 1.00 |
124.67 ± 2.52 |
| Tear Resistance (N) |
16.10 ± 1.17 |
4.47 ± 0.51 |
10.55 ± 1.69 |
6.71 ± 0.42 |
| Tensile Strength (MPa) |
57.23 ± 4.18 |
12.23 ± 1.40 |
38.64 ± 5.72 |
18.35 ± 0.60 |
| % Elongation |
20.85 ± 3.24 |
21.75 ± 5.24 |
32.87 ± 3.22 |
34.23 ± 2.00 |
| Elasticity Modulus (MPa) |
1284.00 ± 86.55 |
285.82 ± 23.95 |
674.84 ± 67.65 |
241.77 ± 55.42 |
Data is shown as mean + standard deviation, n=3
* using Brookfield DV-I Viscometer (S28 spindle and 100 rpm in room temperature) |
