Particle
Number of particles per mL
Serum concentration in the respective DLS experiment in mg/mL
Number of particles per mg serum protein (NP/SP)
in vivo
Number of particles per mg serum protein (NP/SP) DLS
c
s,iv
c
s,conc
NP/SP
iv
NP/SP
conc
PS-LUT
1.02·10
14
6
60
8.5·10
10
8.5·10
10
8.5·10
9
PS-LUT-COOH
2.5·10
15
6
60
2·10
12
2·10
12
1.7·10
11
PS-LUT-NH
2
1.02·10
14
6
60
8.5·10
10
8.5 10
10
8.5·10
9
PS-SDS
4.8·10
13
6
60
4·10
10
4·10
10
3.3·10
8
Table 2:
Comparison of particle and serum concentrations.