Concentration Chromosome break (%) Chromosome gap (%) Chromatid break (%) Chromatid Gap (%) Other aberration (%) Control 0 0 0 0.029 ± 0.029 0 DMSO 1% 0 0 0.087 ± 0.043 0.022 ± 0.031 0 Positive control 0 0 1.333 ± 0.038* 0.696 ± 0.066* 0.014 ± 0.015 MRGO (100µg/ml) 0 0 0 0.014 ± 0.015 0 MRGO (600µg/ml) 0 0.014 ± 0.246 0.246 ± 0.077 0.087 ± 0.066 0

Table 1: Percentage of chromosomal aberration in MRGO treated PBMNCs. * indicates a p value ≤0.05 which was considered significant.