Figure 5: Expression of HO-1 protein level from ischemic brain tissue of PBStreated vehicle (closed bars) or statin (20 mg·kg-1 simvastatin or 10 mg·kg-1 atorvastatin daily for 14 days)-treated rats after 3, 12 and 24 h of pMCAO. The percentage of HO-1 expression at each time is normalized versus the expression (100%) measured after 3 h of untreated ischemia. All values are mean ± SEM of n=6. *P< 0.05 vs. vehicle-pre-treated group.