Bacterial strains Free N-Acetylcysteine (mg/L) Liposomal N-Acetylcysteine (mg/L) MIC MBC MIC MBC PA ATCC 25619 >10000 >10000 >500 5000 PA 13572 5000 5000 1250 2500 PA 5 5000 5000 1250 2500 PA 13641-2 (M) 5000 5000 1250 2500 PA 7 5000 10000 5000 >5000 PA 13639-2 5000 10000 5000 >5000 PA 3 5000 5000 1250 2500 PA ATCC 27853 5000 10000 5000 5000 PA 13640 (M) 5000 >10000 5000 >5000 PA 11 5000 5000 1250 2500 PA ATCC 10145 5000 >10000 5000 >5000 PA 12 5000 5000 1250 2500 PA 13639-1 (M) 5000 >10000 5000 >5000 PA 48913 5000 5000 1250 2500 PA 26250 (M) 5000 5000 1250 2500 PA 1 5000 5000 1250 2500 PA 48912-2 5000 5000 1250 2500 PA 48912-1 5000 10000 5000 5000 PA 8 5000 >10000 5000 5000 PA 13641-1 PAO1 5000 5000 10000 10000 5000 5000 5000 5000

Table 1: In vitro activities of free and liposomal NAC against P. aeruginosa strains