Figure 4: The influence of Ag-NPs on the barrier integrity of PBCEC and PCPEC. A) TER values after treatment of triplicate PBCEC monolayers with AgEO- and AgCitrate-NPs for 24 h. The values are relative to their respective starting value prior to NP addition. The data are expressed as means ± SEM, n ≥ 5. The absolute TER values ranged between 600 and 1000 Ω∙cm2. B) FITC-Dextrane permeability after treatment of triplicate PBCEC monolayers with AgEO- and AgCitrate-NPs for 24 h. The data are expressed as means ± SD of a single measurement. n=3. The absolute TER values ranged between 600 and 1000 Ω∙cm2. C) TER values after treatment of triplicate PCPEC monolayers with AgEO- and AgCitrate-NPs for 24 h. The values are relative to their respective starting value prior to NP addition. The data are expressed as means ± SEM, n = 3. The absolute TER values ranged between 600 and 1000 Ω∙cm2. D) FITC-Dextrane permeability after treatment of triplicate PCPEC monolayers with AgEO- and AgCitrate-NPs for 24 h. The data are expressed as means ± SD of a single measurement. n=3. The absolute TER values ranged between 600 and 1000 Ω∙cm2.