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Figure 10: Restoration of dystrophin in TA muscles of mdx mice (aged 4-6 weeks) 5 days after i.m. injection. A) GFP expression illustrated under fluorescent microscopy. B) Numbers of GFP-positive fibers after treatment of 10 µg pDNA with 2 µg polymers. The maximum numbers of GFP-positive fibers were counted in a single cross-section (n=5, two tailed t-test, * p< 0.05 compared with GFP only). |