Figure 4: Probability density of guest molecules in simplified CMS nanotransporters with A, mPEG outer shell or B, with Glu outer shell. The curves show the most probable position of the guest molecules (dotted line: Nile red, solid line: morphine, dash-dotted line: morphine-H+) inside the CMS nanotransporters once they are loaded (conditional probability, total probability = 1).