Figure 5: CXCL2 expression in mice treated with silica particles. BALB/c mice were injected intravenously with nSP70 (0.2, 0.4, or 0.8 mg/mouse), nSP300 (0.8 mg/mouse), mSP1000 (0.8 mg/mouse), or saline. BALB/c mice with no treatment were divided into untreated group. (A) The plasma concentrations of CXCL2 were determined by ELISA 24 h after treatment. (B) The concentration of CXCL2 in livers of mice was determined by ELISA 24 h after nSP70 injection (0.8 mg/mouse). Data are presented as mean ± SEM; n = 5–6; **P < 0.01 vs salinetreated group; *P < 0.05 vs saline-treated group; ND, not detected.