Figure 6: Confocal microscopy images of HER2-positive BT474 and HER2- negative MDA-MB-231cells treated with Doc-NPs (left column) or Doc -NPsscFv (between column). The nuclei were stained blue with Hoechst. The right column showed the merged images of Alexa 546 and the Hoechst channels. BT474 cells exposed to Doc-NPs-scFv at 100 g/ml for 30 min.