System design Detection strategy LOD Target  
Lateral flow strip through dual immunoreactions Lateral flow dipstick; visual detection < 1 fM R156H-mutant gene of keratin 10 in Epiderm-olytic hyperkeratosis [131]
Glass-silicon hybrid includes a nanoliter liquid injector, a sample mixing, a positioning system, a tempe-rature-controlled reaction chamber, an electrophoretic separation system, and a fluorescence detector Electrophoretical Not specified Not specified  
Integrated, stacked microlaboratory; fabricated by orderly laminating several different functional layers (all 76 x 76 mm2) ; SDA module (76 x 298.5 mm2) consists of a denaturation chamber, an amplification chamber, two pinch, two peristaltic pumps, and an electronic control circuit for fluidic and thermal control Electric-field-driven immunoassay Not specified Shiga-like toxin gene (SLT1) from E. coli [133]
Microchip array; electronic anchoring of sets of amplification primers in distinct areas Fluorescence-based by an electronic hybridization assay Not specified Chlamydia; E. coli parC; Pseudomonas; Salmonella; E. coli gyrA [134]
Table 5: Comparison between different SDA devices.