System design |
Detection strategy |
LOD |
Target |
|
Lateral flow strip through dual immunoreactions |
Lateral flow dipstick; visual detection |
< 1 fM |
R156H-mutant gene of keratin 10 in Epiderm-olytic hyperkeratosis |
[131] |
Glass-silicon hybrid includes a nanoliter liquid injector, a sample mixing, a positioning system, a tempe-rature-controlled reaction chamber, an electrophoretic separation system, and a fluorescence detector |
Electrophoretical |
Not specified |
Not specified |
|
Integrated, stacked microlaboratory; fabricated by orderly laminating several different functional layers (all 76 x 76 mm2) ; SDA module (76 x 298.5 mm2) consists of a denaturation chamber, an amplification chamber, two pinch, two peristaltic pumps, and an electronic control circuit for fluidic and thermal control |
Electric-field-driven immunoassay |
Not specified |
Shiga-like toxin gene (SLT1) from E. coli |
[133] |
Microchip array; electronic anchoring of sets of amplification primers in distinct areas |
Fluorescence-based by an electronic hybridization assay |
Not specified |
Chlamydia; E. coli parC; Pseudomonas; Salmonella; E. coli gyrA |
[134] |