Variables Session 1 Session 2 Session 3
  C ZnONPs C ZnONPs C ZnONPs
Locomotion in the peripheral part (s) 172.16 ± <13.3 194.5 ± 16.4 104 ± 8.6 112.7 ± 13.4 71.16 ± 7.14 113.5 ± 22.1
Locomotion in the central part (s) 2.83 ± 1.7 5.7 ± 2.4 0.83 ± 0.54 2.66 ± 1.7 0.5 ± 0.5 2.83 ± 1.8
Immobility time (s) 100.3 ± 14 81.5 ± 18.56 171.5 ± 8.7 172 ± 12.54 213.16 ± 6.7 165 ± 26.8
Time of contact with objects (s) 19 ± 3.6 18.33 ± 2.66 18.16 ± 2 12.83 ± 2.18 15.16 ± 3.12 8.66 ± 4.62
Number of contact with objects 10.83 ± 1.53 11.83 ± 2.4 9.16 ± 1.16 7.83 ± 0.94 7.66 ± 1.7 9 ± 1.77
Data represent the means ± SEM of 6 animals per group
Table 2: Effects of ZnO-NPs treatment on the open field parameters.