Figure 7 : Tumor volume increase after administration of fenretinide. SK-SAN neuroblastoma cell lines were established as xenografts in athymic nude mice. When the tumors reached a mean volume of 150 mm3 the animals were gavaged with HPR-NC3 (E/D=3) at 100 mg/kg 3 days /week for a total of 3 weeks either in feeding or fasting conditions.