Figure 5: The basic scheme of developing the physical cross-linked hydrogel of NaCMC (sodium carboxymethylcellulose) in the form of reversible gel by heatingcooling a polymer solution. (A) Random coils of the polymer chains after warming up the mixture; (B) (double) Helixes formation (coil-helix transition) upon decreasing the temperature, (C) A rearrangement in rigid helical rods by forming junction zones (hydrogen bonding). Electrostatic repulsion between the carboxyl groups of NaCMC results in an elevated level of gel elasticity.