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Figure 5: Diagram of the attachment-detachment cycle between myosin heads (M) and actin filaments (A), constructed based on biochemical studies on actomyosin ATPase reactions [16]. Note that power stroke, associated with reaction AM·ADP·Pi → AM + ADP + Pi, is produced by myosin heads attached to actin filaments (Figure 5A―B), while myosin heads are detached from actin filaments during recovery stroke, associated with reaction M + ATP → M·ADP·Pi, takes place [24]. |