Dosimetric Parameter SIB SB P Value Minimum Dose (Gy) 37.82 36.57 0.15 Maximum Dose (Gy) 53.55 56.08 <0.01 Mean Dose (Gy) 44.81 42.83 0.02 V95 (%) 99.38 97.3 0.01 V100 (%) 98.29 95.27 <0.01 V110 (%) 5.87 14.78 <0.01 Conformity Index 0.97 0.94 0.01 Homogeneity Index 0.09 0.14 0.01

Table 2b: Comparison of boost volume coverage parameter (Mean) for SIB boost and Sequential boost methods of intact breast cancer patients (Prescribed Dose 48 Gy).