Pneumonitis Grade Definition 1 Asymptomatic; clinical or diagnostic observations only; intervention not indicated 2 Symptomatic; medical intervention indicated; limiting instrumental ADL 3 Severe symptoms; limiting self care ADL; oxygen indicated 4 Life-threatening respiratory compromise; urgent intervention indicated (e.g., tracheotomy or intubation) 5 Death Abbreviations: ADL: Activity of Daily Living

Table 1: Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0 grading scale for pneumonitis.