Characteristics Value or No. of Patients (%) (N=762) Age at diagnosis, years        Median 64      Mean 63.2      Range 25-87 Gender        Male 643 (84%)      Female 119 (16%) KPS        80-100 685 (90%)      40-70 75 (10%) Histology        Adeno 585 (76%)      SCC 165 (22%)      Other 12 (2%) Tumor Differentiation        Well 10 (1%)      Moderate 310 (43%)      Poor 403 (56%) Overall Clinical Stage        1 13 (2%)      2 259 (35%)      3 412 (56%)      4a 56 (7%) Induction Chemo        Yes 305 (40%)      No 457 (60%) Radiation Modality        3DCRT 326 (43%)      IMRT 316 (41%)      PBT 120 (16%) Surgery        Yes 379 (50%)      No 383 (50%)

Table 1: Baseline patient and treatment factors. Abbreviations: KPS: Karnofsky Performance Status Score; Adeno: Adenocarcinoma; SCC, Squamous Cell Carcinoma; 3D CRT: Three-Dimensional Conformal Radiation Therapy; IMRT: Intensity-Modulated Radiation Therapy; PBT: Proton Beam Therapy.