Figure 1: Time course of development of mechanical allodynia and thermal hyperalgesia in CCI rats compared to sham operated rats after operation. Mechanical withdrawal threshold (MWT) and Thermal withdrawal latency (TWL) are shown as mean± S.E. A significant reduction in MWT and TWL in CCI group compared with sham group at 10 days after operation. Statistical analysis was performed using Student’s t-test and p-values <0.05 were regarded as statistically significant. *p<0.05, **p<0.01 VS sham group (n=8).