Thrombolysis

No Thrombolysis

 

MEN

WOMEN

p<

MEN

WOMEN

P<

Mean age

68.18 (n=154)

73.66 (n=155)

0.001

67.02 (n=526)

74.69 (n=514)

0.001

Mean NIH score at admission

10.62 (n=149)

11.50 (n=153)

0.163

6.72 (n=528)

9.04 (n=577)

0.001

Mean NIH score at discharge

6.53   (n=147)

7.66 (n=144)

0.463

5.21 (n=514)

6.64 (n=542)

0.004

Patients with NIH score 0-7 at admission

36.7 % (54/147)

32.2 % (46/143)

0414

 68.2 % (360/528)

 57.9 % (334/577)

0.001

Patients with NIH score 8-14 at admission

34.7 % (51/147)

37.1 % (53/143)

0.675

18.4 %  (97/528)

19.6 %  (113/577)

0.609

Patients with NIH score over 15 at admission

28.6 % (42/147)

30.8 % (44/143)

0.683

10.8 %  (57/528)

 20.9 % (121/577)

0.001

mRS 3 months outcome ≦ 2

60.7 % (34/56)

60% (27/45)

0.942

65.3% (209/320)

63.4% (226/356)

0.620

mRS 3 months outcome

1.6 (range0-6)

2.5(range 0-6)

 

1.83 (range0-6)

1.86 (range0-6)

0.702

Door  to needle time

51.71 min (n=152)

56.14 min (n=145)

0.082

---

----

----

Time from onset to stroke unit

153 min

154 min

0.384

787.38 min

791.22 min

0.221

Stroke subtype

 

 

 

 

 

  • Lacunar syndrome

14.5 % (22/152)

9.6 % (14/145)

0.204

17.1 % (91/531)

11.9 % (69/579)

0.014

  • Total anterior circulation syndrome

10.5 % (16/152)

18.6 % (27/145)

0.048

7.3 % (39/531)

10.9 % (63/579)

0.043

  • Partial anterior circulation syndrome

68.4 % (104/152)

67.6 % (98/145)

0.878

45.01 % (239/531)

53.7 % (311/579)

0.005

  • Posterior circulation syndrome

5.9 % (9/152)

4.1 % (6/145)

0.483

29.4 % (156/531)

22.8 % (132/579)

0.013

  • Obscure

0.6 % (1/152)

0 % (0/145)

0.328

0.7 % (4/531)

0.7 % (4/579)

0.903

Lokalization

 

 

 

 

 

  • Left hemisphere

53.9 % (82/152)

54.5 % (79/145)

0.927

39.9 %  (12/579)

40.1 % (232/579)

0.961

  • Right hemisphere

40.8 % (62/152)

40.7 % (59/145)

0.986

31.1 % (165/531)

36.9 % (214/579)

0.040

  • Both hemispheres

0.6 % (1/152)

0.0 %  (0/145)

0.329

0.37 % (2/513)

0.51 % (3/579)

0.726

  • Brainstem

 3.3 % (5/152)

4.8 %  (7/145)

0.502

22.03 % (117/531)

17.44 % (101/579)

0.550

  • Cerebellum

 1.3 % (2/154)

0.0 % (0/154)

0.167

6.21 % (33/531)

5.01 % (29/579)

0.383

Etiology of stroke

 

 

 

 

 

  • Microangiopathy

16.5% (25/151)

20% (25/145)

0.876

100 % (531/531)

100% (579/579)

 

  • Thrombembolism

15.5 % (30/193)

18.2 % (34/186)

0.478

25.6 % (136/531)

25.6 % (148/579)

0.986

  • Macroangiopathy

55.4 % (107/193)

59.7 % (111/186)

0.691

45.2 % (240/531)

54.05 % (313/579)

0.005

  • Haemodynamic

40.4 % (78/193)

28.5 % (22/186)

0.020

42.6 % (226/531)

36.8 % (213/579)

0.130

  • Koagulopathy

8.3 % (16/193)

5.9 % (11/186)

0.370

8.1 % (43/513)

9.7 % (56/579)

0.359

Thrombolysis treatment

50.9 % (193/379)

49.1 % (186/379)

 

----

-----

---

Table 1: Demographics and baseline characteristics of men and women treated with and without IV Thrombolysis.