| PVL Location |
PVL Volume**
or Count |
RRMS (n=36) |
CIS (n=10) |
Migraine (n=32) |
| Mean ± SEM (mm3) |
P-value (RR-MS
vs Migraine) |
Mean ± SEM (mm3) |
P-value (CIS vs
Migraine) |
Mean ± SEM (mm3) |
| T2WI |
|
|
|
|
|
|
| Anterior Horn |
Volume |
268.2 ± 39.04 |
0.2589 |
225.7 ± 64.84 |
0.7788 |
200.8 ± 44.87 |
| Anterior Horn |
Count |
1.583 ± 0.1457 |
0.3477 |
1.600 ± 0.3712 |
0.5376 |
1.375 ± 0.1665 |
| Posterior Horn |
Volume |
470.4 ± 90.61 |
0.0325*** |
829.5 ± 437.6 |
0.0228 |
250.6 ± 31.32 |
| Posterior Horn |
Count |
1.306 ± 0.1248 |
0.2228 |
1.500 ± 0.2687 |
0.9127 |
1.531 ± 0.1346 |
| Body of Lateral |
Volume |
838.5 ± 178.8 |
0.0005 |
857.5 ± 509.6 |
0.0149 |
138.3 ± 30.90 |
| Ventricles |
|
|
|
|
|
|
| Body of Lateral |
Count |
2.444 ± 0.3198 |
0.0002 |
1.500 ± 0.4534 |
0.1657 |
0.9375 ± 0.1735 |
| Ventricles |
|
|
|
|
|
|
| Temporal Horn |
Volume |
16.28 ± 9.756 |
0.133 |
15.53 ± 11.06 |
0.4066 |
69.92 ± 35.79 |
| Temporal Horn |
Count |
0.139 ± 0.070 |
0.0097 |
0.2000 ± 0.1333 |
0.1986 |
0.5313± 0.1346 |
| FLAIR |
|
|
|
|
|
|
| Anterior Horn |
Volume |
415.7 ± 43.26 |
0.256 |
393.5 ± 108.3 |
0.3946 |
498.6 ± 59.35 |
| Anterior Horn |
Count |
2.250 ± 0.1220 |
0.5494 |
2.100 ± 0.2769 |
0.4309 |
2.375 ± 0.1724 |
| Posterior Horn |
Volume |
1405 ± 314.8 |
0.0011 |
1311 ± 725.9 |
0.0132 |
253.6 ± 56.20 |
| Posterior Horn |
Count |
1.528 ± 0.1290 |
0.0037 |
1.200 ± 0.3266 |
0.3999 |
0.9063 ± 0.1641 |
| Body of Lateral |
Volume |
1802 ± 384.3 |
0.0005 |
2578 ± 1538 |
0.0096 |
290.1 ± 55.70 |
| Ventricles |
|
|
|
|
|
|
| Body of Lateral |
Count |
2.944 ± 0.2899 |
0.0019 |
2.000 ± 0.5774 |
0.5351 |
1.625 ± 0.2831 |
| Ventricles |
|
|
|
|
|
|
| Temporal Horn |
Volume |
49.17 ± 21.29 |
0.3043 |
543.7 ± 543.7 |
0.086 |
21.15 ± 15.79 |
| Temporal Horn |
Count |
0.2500 ± 0.09237 |
0.4207 |
0.1000 ± 0.1000 |
0.6666 |
0.1563 ± 0.06521 |
* PVL = Periventricular Lesions
** T2WI and FLAIR images were analyzed using JIM version 5.0 software to measure PVL volume. Unpaired t-test was used for statistical analysis and calculation of
p-value.
*** P-values in bold are considered statistically significant. |
