| Nimodipine dose |
Seizure freedom
n(%) |
More than 50% of seizure rate reduction but not seizure free* |
Lack of efficacy*n(%) |
| Intention to treat analysis |
| Arm B n=13
(3 mg/kg/day) |
2 (15.3) |
8 (61.5) |
2 (15.3) |
| Arm A n=13
(2 mg/kg/day) |
----------- |
8 (61.5) |
5 (38.4) |
| Total = 26 |
2 (7.69) |
16 (61.5) |
7(26.9) |
| Per protocol analysis |
| Arm B n=12
(3 mg/kg/day) |
2 (16.7) |
9 (75) |
1 (8.3) |
| Arm A n=10
(2 mg/kg/day) |
------------ |
7 (70) |
2 (20) |
| Total = 22 |
2 (9.1) |
16 (72.7) |
3 (13.6) |
*differences between proportion of patients with more than 50 % of seizure free, lack of efficacy and seizure freedom p>0.05 (Chi squared test). |
