Table 2

Compound	Total GSH TC₅₀ (mM)	Percent Change in Total GSH	Membrane Lipid Peroxidation	Caspase 3 Activity (Index/Dose)
J-147	217	-84.9	0	NC
Rotenone	0.3	-100.0	0	NC
Camptothecin	3.9	-64.5	1	3/1

Glutathione (GSH) Data:
Decrease in Total GSH indicated by (-).
Increase in Total GSH indicated by (+).
Membrane Lipid Peroxidation Data:
0=No Change,
1=Modest increase with maximum values<15 pg/mL,
2=Concentration related increase with maximum values>15 pg/mL,
3=Concentration related increase with a maximum value>30 pg/mL.
Caspase 3 Data:
0-200=1, 200-400=2, 400-600=3, 600-800=4, 800-1000=5, 1000-1200=6, 1200-
1400=7, 1400-1600=8, 1600-1800=9, 1800-2000=10.

Table 2: Comparison of J-147 with Control compounds on Oxidative Stress and Apoptotic Cell death.