| Author |
Agent and Application |
Patient Collective |
Results |
Methodical Side Effects |
Pharmacological Side Effects |
Remark |
| Dalbasti et al., [95] |
Papaverin pellets intraoperative positioning of pellets |
117 patients with high risk of vasospasm (73 treatment, 44 control) |
marked reduction of vasospsm, significant improvement of outcome |
None |
None |
No randomisation |
| Kasuya et al., [96] |
Nicardipin pellets, intraoperative positioning of pellets |
125 patients with high risk of vasospasm (97 treatment, 28 control) |
mignificant reduction of DIND |
None |
None |
No randomisation |
| Krischek et al., [97] |
Nicardipine pellets intraoperative positioning of pellets |
100 patients with high risk of vasospasm (Fisher grade 2 und 3) |
7 patients with DIND, 5 patients with DCI.
No spasms in vicinity to pellets |
None |
None |
No randomisation |
| Barth et al., [98] |
Nicardipine pellets, intraoperative positioning of pellets |
32 patients (16 treatment, 16 control) |
reduction of angiographic vasospasm and DIND, improvement of neurological outcome |
None |
None |
Randomized study |
