Figure 4: Blast overpressure dose-response following compressed-air driven blast exposure. (A) Representative bands from Western blots used to quantify IgG levels in the ipsilateral ventral cortex (IVX), cerebellum (CBM), and brain stem (BS). Samples were separated by electrophoresis in an order alternative to the one presented here to decrease inter-lane variability, however all blots shown here were imaged concurrently, and cropped to be repositioned as shown here. No other image modifications were made. (B) Diagram showing location of cuts made to separate cerebrum into ipsilateral ventral cortex (IVX), contralateral ventral cortex (CVX), ipsilateral dorsal cortex (IDX), and contralateral dorsal cortex (CDX). (C) Average IgG levels compared to actin levels in the IVX of animals exposed to increasing blast overpressure. (D) Average IgG levels compared to actin levels in the CBM of animals exposed to increasing blast overpressure. €. Average IgG levels compared to actin levels in the BS of animals exposed to increasing blast overpressure. One-way ANOVA, n=4 per treatment group.