Figure 5: IVX IgG:Actin ratios as a function of peak overpressure and impulse exposure. (A) Peak blast overpressure exposure vs. IgG:Actin ratio separated by shockwave source. There appears to be a threshold effect whereby animals exhibiting IgG:Actin ratios above 0.1 were also mostly exposed to peak overpressures of 150kPa or greater. (B) Peak blast impulse exposure vs. IgG:Actin ratio separated by shockwave source. There was no positive effect of impulse on IgG extravasation for animals exposed to compressed air- or oxyhydrogen-driven shockwaves. (C) Peak blast overpressure exposure vs. IgG:Actin ratio. A positive correlation between the amount of IgG as detected by Western blot analysis and the peak overpressure to which the animals were exposed was evident. (D) Peak blast impulse exposure vs. IgG:Actin ratio. Though there was a general positive trend in the relationship between impulse and IgG extravasation, the relationship was not statistically significant. Pearson correlation, two-tailed. n=6 or 19 (A and B) or n=25 (C and D) per treatment group.