PD- pain(+) (n=68)yes (%) PD- pain(-) (n=74)yes (%) Control (n=54)yes(%) P 1 value P2 value P3 value
1.Dribbling 13(19.1) 15(20.3) 2(3.7) 0.863 0.012 0.006
2.Loss of Taste/Smell 18(26.5) 14(18.9) 2(3.7) 0.282 0.001 0.010
3.Swallowing/Choking    difficulties 5(7.4) 11(14.9) 1(1.9) 0.268 0.002 0.013
4.Nausea/Vomiting 3(4.4) 2(2.7) 3(5.6) 0.581 0.772 0.411
5.Constipation 38(55.9) 40(54.1) 9(16.7) 0.827 0.000 0.000
6.Bowel incontinence 2(2.9) 1(1.4) 1(1.9) 0.510 0.700 0.822
7.Bowel emptying incomplete 16(23.5) 16(21.6) 4(7.4) 0.786 0.017 0.029
8.Urgency 17(25.0) 14(18.9) 10(18.5) 0.381 0.392 0.954
9.Nocturia 20(29.4) 23(31.1) 9(16.7) 0.829 0.100 0.063
10.Pains 32(47.1) 0(0) 16(29.6) 0.000 0.050 0.000
11.Weight loss 10(14.7) 1(1.4) 1(1.9) 0.003 0.014 0.822
12.Remembering 35(51.5) 17(23.0) 18(33.3) 0.000 0.045 0.194
13.Loss of interest 23(33.8) 15(20.3) 0(0.0) 0.068 0.000 0.000
14.Halucinations Delusions 6(8.82) 4(5.4) 1(1.9) 0.426 0.100 0.305
15.Concentrating 15 (22.1) 8(10.8) 0(0.0) 0.069 0.000 0.013
16. Sad, blues 26(38.2) 17(23.0) 3(5.6) 0.048 0.000 0.007
17. Anxiety 14(20.6) 11(14.9) 3(5.6) 0.371 0.017 0.096
18. Sex_drive 5(7.4) 3(4.1) 2(3.7) 0.394 0.015 0.013
19. Sex_difficulty 7(10.3) 2(2.7) 2(3.7) 0.064 0.017 0.012
20. Dizziness 18(26.5) 13(17.6) 8(14.8) 0.200 0.118 0.626
21. Falling 8(11.7) 12(16.2) 3(5.6) 0.446 0.234 0.064
22. Daytime sleepiness 11(16.2) 10(13.5) 3(5.6) 0.655 0.068 0.141
23. Insomnia 26(38.2) 12(16.2) 10(18.5) 0.003 0.018 0.733
24. Intense, vivid dreams 29(42.7) 21(28.4) 5(9.3) 0.075 0.000 0.008
25.Acting out during dreams 20(29.4) 22(29.7) 3(5.6) 0.967 0.001 0.001
26. Restless legs 23(33.8) 14(18.9) 11(20.4) 0.043 0.100 0.838
27.Swelling 14(20.6) 5(6.8) 4(7.4) 0.016 0.041 0.887
28.Sweating 20(29.4) 15(20.3) 8(14.8) 0.207 0.057 0.427
29.Diplopia 6(8.8) 3(4.1) 3(5.6) 0.244 0.493 0.691
30. Delusions 0 0 0 constant constant constant
Table 2: Percentage of non-motor manifestations in PD patients with and without pain and in controls, P1: differences between PD patients with pain and without pain; P2: differences between PD patients with pain and controls; P3: differences between PD patients without pain and controls.