Figure 2: Quantitative tPA-STOP and PAI-1 inhibition analysis: Quantitation of the extent of tPA activity (Change in OD) inhibition by tPA-STOP (5 μM) and PAI-1 (0.25 μM). Both tPASTOP and PAI-1 significantly (p<0.001) inhibit tPA activity by 83-98% compared to control (p<0.001) Black bars- 5 minute OD reading; Grey bars- 10 minute OD reading.