NCT Route Dose Times Masking EDSS Selection criteria Out-comes
01377870 IV ? Single DB 3-6.5 D AE, EDSS, MSFC, RAO, B-C. MRI, QOL
01895439 IV ? Single OL <=6 ND AE, B.MRI, OPHTHALMIC TESTS
01883661 IV ? 6 in one month OL ? ND AE, EDSS, QOL, B.MRI, CSF, VEP
01844957 IV 1-2x10(6)/kg Single DB 3-6.5 D B.MRI, Relapse, EDSS
01364246 IV ? ? OL ? ND AE, EDSS, BAER, SSEP, VEP, B.MRI
01730547 IV ? ? DB 3-6.5 D AE, B.MRI, Relapse, Disability progression
01056471 IV 10(6), 4x10(6)/kg Single DB >=5.5, <=9 D AE, B.MRI, IMMUNOLOGY, NEUROPHYSIOLOGY, NEUROPSYCHOLOGY
01228266 IV 2x10(6)/kg Single DB 3-6.5 D AE, Clinical, B.MRI, OCT, IMMUNOLOGY, GOL
00813969 IV 2x10(6)/kg Single OL 3-6.5 D AE, B.MRI, Disease activity
01745783 IV 2x10(6)/kg Single DB ? D AE, B.MRI, EDSS, MSFC, QOL, Disease free patients
01933802 IV 2-10x10(6)/kg 3 each three months OL >=3 D AE, Evoked potentials, QOL, EDSS, MSFC, B.MRI
01606215 IV 2x10(6)/kg Single DB 3-6.5 D AE, B.MRI, MSFC, EDSS, IMMUNOLOGY
----------- IV 1-2x10(6)/kg Single DB 3-6.5 D ?
01453764 IV, IT ? Single OL ? ND AE, EDSS, Relapse
01932593 IV ? Single OL ? ND AE, Evoked potentials, B.MRI, EDSS, MSFC, MSIS-29
00927108 ? ? ? OL ? ND ?
01815632 IV 1.5X10x8/kg Twice DB 4.0-6.0 D Global EP, Safety, EDSS, MSIS, MSFC, B-C. MRI, OCT
Table 5: International ongoing clinical trials of the Stem Cell-Based Therapy in MS: Study designs;