Figure 1: Abnormal Patterns in Synchrony Before and During Seizures. Top left: Time series of EEG activity recorded by intracranial electrodes in an epileptic patient. Right: Illustration of the gross anatomical regions of the electrode recordings (above: left temporal lobe; below: left hippocampus). Dashed line marks the onset of the epileptic seizure (ictal onset). Bottom left: Time series of correlation between the simultaneous EEG activity in the left temporal pole and the left hippocampus. Normal levels of neural synchronization (in green shading) leading to the abnormally low levels of neural synchronization (desynchronization, in yellow), and heightened levels of neural synchronization as described in classical work on epilepsy (blue). Adapted with permission from Jiruska et al. (2013)[11].