FA means (n=14) P values (95% CI) *
Region of Interest (ROI) Pre- transplant Post- Transplant  
Piramidal tract total 0.433 0.448 0.05 (-0.035 to -0.000)
Piramidal tract left 0.433 0.448 0.05 (-0.03 to -0.000)
Piramidal tract right 0.433 0.448 0.07 (-0.373 to -0.001)
Bulbar region total (ROI 1) 0.429 0.440 0.20 (-0.034 to -0.008)
Bulbar region right (ROI 1) 0.427 0.439 0.22 (-0.382 to -0.009)
Bulbar region left  (ROI 1) 0.431 0.442 0.20 (-0.031 to -0.007)
Mesencephalic region total (ROI 2) 0.511 0.524 0.18 (-0.038 to -0.008)
Mesencephalic region right (ROI 2) 0.507 0.519 0.31 (-0.038 to -0.013)
Mesencephalic region left (ROI 2) 0.514 0.530 0.10 (-0.041 to -0.002)
Internal capsule region total (ROI 3) 0.513 0.532 0.03 (-0.041 to -0.002)
Internal capsule region right (ROI 3) 0.509 0.525 0.04 (-0.036 to -0.000)
Internal capsule region left (ROI 3) 0.517 0.539 0.05 (-0.051 to -0.000)
Corona radiata region total (ROI 4) 0.366 0.384 0.05 (-0.410 to -0.000)
Corona radiata region right (ROI 4) 0.370 0.390 0.07 (-0.484 to -0.002)
Corona radiata region left (ROI 4) 0.362 0.377 0.04 (-0.348 to -0.000)
Table 2: Fractional Anisotropy (FA) in cerebral regions of interest (ROI). Comparison of the FA values in different ROI in ALS subjects before and after stem cell transplantation into the frontal motor cortices; * 95% Confidence Interval