Study Period  Number of patients    Total Responders 21 Partial Responders   Period from 7 months to 12months 1 Period from 7months to 18months 2 Period from 13monthsto 24 months 4 Non- responders 11

Table 2: Responder rate (≥50% reduction of seizure)at 3 study periods; Total Responders:  ≥ 50% reduction of seizure frequency in all three study periods; Partial Responders: ≥ 50% reduction of seizure frequency in < three study periods; Non-responders: < 50% reduction of seizure frequency in all three study periods.