Figure 1: TH-immunoreactive (-ir) fibers in the frontal cortex, area 2 of 8-day-old pup following maternal exposure to RCS. (A, C) A control rat. (B, D) A prenatal RCS rat. The quantity of TH-ir fibers is lower in the prenatally RCS rat, especially in layers II and III. Cortical TH-ir fibers of RCS show a reduced number of large varicosities. An arrow indicates a varicose fiber of the control rat. Bar: 25µm.