Figure 1: The monocyte chemoattractant protein-1(MCP-1), NeuNand glial fibrillary acidic protein (GFAP) immunostatining andbrain edema index (BEI) among the groups. Upper panel representsMCP-1(+) monocytes ( Red arrow head), NeuN (+) neurons (whitearrow head) with vacuolated neucli and GFAP(+) astrocytes(yellow head) immunostaining of the sham-operated group (A), theSAH only group (B), the SAH rats treated with vehicle (C),500ug/kg/day parecoxib treatment SAH group (D), 1000ug/kg/dayparecoxib treatment in SAH rats (E) and SAH animals received2000ug/kg/day parecoxib treatment (F). Standard bar= 400um.Vacuolar formation (white arrow head) was observed in neurons inSAH groups, which was absent in the sham-operated and parecoxibtreatment SAH groups. Standard bar= 50um. Lower panel revealedthe brain edema index. Data in the figure are presented as mean ±SD. (#, ##, ###:P>0.01, indicates comparison among the500/1000/2000ug/kg/day parecoxib treatment and SAH groupsrespectively).