Figure 5: Levels of cleaved caspase-3 and -9a in the SAH rats receiving parecoxib treatment (rt-PCR). Top panel: all groups are the same as those stated in the legend of Fig.3. 2000ug/kg parecoxib significantly decreased caspase-9a in the SAH rats (p<0.01). The bar graphs revealed 1000ug/kg and 2000ug/kg parecoxib decreased caspase-3 level when compared with the SAH groups. Parecoxib, at high dose, can attenuate apoptosis-related caspase-9 and caspase-3 when compared with the SAH groups. Data are shown as mean ± SD. (*, **: P<0.01, and #, ##: P>0.01)