Figure 1: The illustration of spinal cord demyelination lesion in T8 and T9 ventral-lateral funiculus (VLF) on mice. A. The mouse is placed in a U-shaped metal channel and the spinal column was fixed with bilateral stabilizers (top panel). The glass micropipette (indicated by white arrowhead) is positioned over the spinal cord surface (dura removed) under a dissecting microscope. B. Red arrowheads on the steric spinal cord model demonstrate the injection sites and the red dots on the transection plane indicate the lesion sites. C & D. Red dots indicate the injection sites on T8, T9 and T10 from top view (C) and on the transection plane of thoracic spinal cord (D).