Figure 4: A) Micrographs of spinal cord sections 14 and 21 days after mice were treated with vehicle, Antp and COG112 compared with sham groups stained by eriochrome cyanine (EC). The area of 21 demyelination in the VLF was indicated by arrows (Bar = 50μm). B) The emyelination area was quantified by image analysis. The lesion size in COG112 treated mice was smaller at days 14 and 21 following injury compared with Antp and vehicle groups (mean ± SEM, * p< 0.05, ** p< 0.01, n=6).