Figure 1: Behavioral scores of mice with chronic progressive EAE induced by MOG injections and treated daily from the time of initiation of disease (day 0) with either saline (vehicle),10 mg/kg OGF, or 0.1 mg naltrexone (LDN). Mean behavioral scores are significantly different from MOG+Vehicle mice at p<0.05 (*), p<0.01 (**), and p<0.001 (***). (Adapted from Rahn et al., [35])