Group

5w

10w

15w

Serum creatinine(umol/L)

Control group(n=5)

49.2±1.9

67±10.2

61.8±6.6

Rhein-treated group(n=7)

44.4±3.5*

50.7±6.6**

45.6±9.0**

Proteinuria(mg/24h)

Control group(n=5)

2.74±1.27

3.25±1.07

3.32±0.68

Rhein-treated group(n=7)

1.09±0.51*

0.41±0.29**

0.37±0.17**