Did the study ask a clearly-focused question?

Yes

Yes

Yes

Yes

Yes

Yes

Qustiones of CASP

ASTRAL

STAR

DRASTIC

EMMA

SNRASCG

RAOOD

1. Did the study ask a clearly-focused question?

Yes

Yes

Yes

Yes

Yes

Yes

2. Was this a randomised controlled trial (RCT) and was it appropriately so?

Yes

Yes

Yes

Yes

Yes

Yes

3-Were participants appropriately allocated to intervention and control groups?

Yes

Yes

Yes

Can’t tell

Can’t tell

Can’t tell

4-Were participants, staff and study personnel ‘blind’ to participants’ study group?

No

No

Can’t tell

No

No

No

5-Were all of the participants who entered trial accounted for at its conclusion?

Yes

Yes

Yes

Yes

Yes

Yes

6-Were the participants in all groups followed up and data collected in the same way?

Yes

Yes

Yes

Yes

Yes

Yes

7-Did the study have enough participants to minimize the play of chance?

Yes

No

No

No

No

No

8-How precise are these results

precise

No

No

No

No

No

9-Were all important outcomes considered so the results can be applied?

No

No

No

No

No

No

Level of evidence

Ib

Ib

Ib

IIb

IIb

IIb

Total questions answered

7

5

5

4

4

4

Table 4: CASP Questionnaire for the selected randomized controlled trails.