Figure 4: Arterial pressure was normalized with nifedipine in saltinduced hypertensive rats. DS 8%: Dahl salt-sensitive rats fed a high-salt diet only; DS 8%-nif: Dahl salt-sensitive rats fed a high-salt diet concomitant with nifedipine (50-62.5 mg/day); DS 0.4%-nif: Dahl salt-sensitive rats fed a regular salt diet concomitant with nifedipine (50-62.5 mg/day). SAP: systolic arterial pressure measured with the tail cuff method in conscious rats (n = 5); Age: rat age. *: p < 0.05 vs. DS-0.4%. Oral nifedipine, a hypotensive drug that acts via calcium antagonism, normalized arterial pressure in salt-induced hypertension [30].