| Parameter |
Patients with HTN
n=13 |
Patients without HTN
n=20 |
P |
| Age [years] |
14.8 (6.4-17.8) |
14.5 (3.7-18.0) |
NS |
| Gender (♂/♀) (n/n, %/%) |
7/6
(53.8% / 46.2%) |
15/5
(75.0% / 25.0%) |
Renal disease (n) (%):
Henoch- Schonlein nephropathy
IgA nephropathy
Membranoproliferative GN
Mesangioproliferative GN
Minimal change disease
FSGS
Other |
1 (7.7%)
3 (23.1%)
3 (23.1%)
3 (23.1%)
0 (0.0%)
2 (15.4%)
1 (7.7%) |
8 (40.0%)
4 (20.0%)
1 (5.0%)
0 (0.0%)
3 (15.0%)
1 (5.0%)
3 (15.0%) |
| Age at the onset of renal disease [years] |
7.9 (1.5-16.3) |
9.6 (0.3-14.8) |
| Duration of renal disease [months] |
22.0 (2.0-144.0) |
33.5 (1.0-155.0) |
| BMI Z-score |
0.2 ± 1.4 |
0.5 ± 1.2 |
| Creatinine [mg/dL] |
0.6 (0.3-10.1) |
0.6 (0.4-1.3) |
| Urea [mg/dL] |
31.0 (14.0-131.9) |
24.0 (10.0-58.0) |
| Uric acid [mg/dL] |
6.5 ± 2.0 |
5.4 ± 2.0 |
| GFR by Schwartz formula [mL/min/1.73m2] |
110.8
(20.8-166.6) |
109.9
(50.4-137.3) |
| Total protein [g/dL] |
6.35 (3.8-7.8) |
7.0 (3.4-8.1) |
P<0.05 |
| Albumin [g/dL] |
3.6 (2.3-4.8) |
4.1 (1.5-4.9) |
P=0.07 |
| Total cholesterol [mg/dL] |
242.7 ± 71.5 |
191.7 ± 41.3 |
P<0.05 |
| Triglycerides [mg/dL] |
155.4 ± 60.4 |
129.4 ± 47.6 |
NS |
| Calcium [mg/dL] |
9.32 ± 1.04 |
9.68 ± 1.24 |
P=0.07 |
| Proteinuria n [%] [mg/kg/24h] |
8 (54.5%)
80.4 (4.5-184.6) |
7 (22.6%)
29.4 (6.7-322.1) |
NS |
Immunosuppressive therapy
Prednisone (n) (%)
Prednisone dose [mg/kg/24h]
Cyclosporin A (n) (%)
Azathioprine (n) (%)
Mycophenolate mofetil (n) (%) |
9 (69.2%)
0.96 (0.04-1.43)
3 (23.1%)
2 (15.4%)
2 (15.4%) |
14 (70.0%)
0.52 (0.03-1.18)
2 (10.0%)
1 (5.0%)
0 (0.0%) |
BMI: Body Mass Index; FSGS: Focal Segmental Glomerulosclerosis; GFR:
Glomerular Filtration Rate; GN: Glomerulonephritis.