| Characteristic |
SRNS
n=40 |
SSNS
n=28 |
Well child
n=31 |
| Age at study, mean (SD) yrs |
8.3(4.5) |
8.5 (3.9) |
12 (3.6) |
| Age at diagnosis, mean(SD) yrs |
5.9 (3.3) |
6.2 (3.2) |
- |
| Sex, n (%) |
|
|
|
| Boys |
31(77.5) |
17 (60.7) |
16 (51.6) |
| Girls |
9 (22.5) |
11 (39.3) |
15 (48.4) |
| Systolic blood pressure, mmHg (SD) |
113.6(14.6) |
103.2 (10.2) |
106.8 (10.8) |
| Diastolic blood pressure, mmHg (SD) |
75.3(12.8) |
65.4 (7.9) |
68.4 (9.3) |
| Serum MIF, median (min-max) ng/mL |
31.9(14.3-117.2)a |
21.8(10.4-31.8) |
24.1 (11.4-31.1) |
| Plasma angiotensin II, median (min-max) pg/mL |
22.8 (3.1-153.4)b |
16.3 (2.9-139.5) |
12.9 (5.5-58.8) |
Patients’ management, n (%)
*Pred + CPA iv
*Pred + CPA oral
*Pred + CsA
*Pulse MP + Pred + CPA oral
*Pred AD only |
22 (55)
14 (35)
2 (5)
2 (5)
- |
-
-
-
-
28 (100) |
- |
| Threshold dose of prednisone at inclusion of study, median (min-max) mg/m2 BSA e.o.d |
33 (16-41)c |
12 (5-34) |
- |
| UACR, mean (SD) μg/mg creatinine |
5898.6 (4289)d |
65.7 (7.5) |
6 (4) |
Abbreviations: SD: Standard Deviation; Pred: Prednisone; CPA= Cyclophosphamide; Csa: Cyclosporine A; Pulse MP: Pulse Methyl Prednisolone; Pred AD: Prednisone
Alternating Days; BSA: Body Surface Area; E.O.D: Every Other Day; UACR: Urinary Albumin Creatinine Ratio
Statistics: ap<0.001 vs. other group (Kruskall Wallis test), bp=0.01 vs. other group (Kruskall Wallis test), cp<0.001vs. SSNS (Mann Whitney), dp<0.001 vs. other group
(Anova) |
